New PDF release: Adjuvant Therapy of Breast Cancer

By Larry Norton (auth.), I. Craig Henderson (eds.)

ISBN-10: 1461365503

ISBN-13: 9781461365501

ISBN-10: 1461534968

ISBN-13: 9781461534969

The result of randomized trials comparing using early or adjuvant systemic remedy for sufferers with resectable breast melanoma offer an eloquent rebuttal to people who could argue that we've got made no development within the remedy of melanoma. a number of the tumors that we've got been so much winning in curing with chemotherapy and different more moderen kinds of remedy are fairly unusual. against this, breast melanoma is still the only commonest malignancy between ladies within the western global, is more and more a explanation for loss of life all through Asia and Third-World international locations, and is still essentially the most giant explanations of melanoma mortality global­ extensive. using mammography as a method of early detection has been proven to minimize breast melanoma mortality through 25-35% between these popu­ lations within which it truly is applied. using adjuvant systemic therapy in acceptable sufferers offers the same (and extra) relief in breast melanoma mortality. Few topics were so systematically studied within the background of medication, and it kind of feels reasonable to finish that the worth to adjuvant systemic treatment in prolonging the lives of girls with breast melanoma is extra firmly supported by way of empirical proof than even the extra traditional or fundamental remedies utilizing numerous mixtures ofsurgery and radiotherapy.

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Extra resources for Adjuvant Therapy of Breast Cancer

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Bruce WR, Meeker BE, and Valeriote FA. Comparison of the sensitivity of normal hematopoietic and transplanted lymphoma colony-forming cells to chemotherapeutic agents administered in vivo. J Nall Cancer Inst 37:233-245, 1966. DeVita VT Jr. Dose-response is alive and well. J Clin Oncol 4:1157-1159, 1986. Tannock IF, Boyd NF, DeBoer G, et al. A randomized trial of two dose levels of cyclophosphamide, methotrexate, and fluorouracil chemotherapy for patients with metastatic breast cancer. J Clin OncoI6:1377-1387, 1988.

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Combination chemotherapy for advanced breast cancer: Response and effect on survival. Ann Intern Med 84:389-392, 1976. 24. Cummings FJ, Gelman R, and Horton J. Comparison of CAF vs. CMFP in metastatic breast cancer: Analysis of prognostic factors. J C1in Oncol 3:932-940, 1985. 25. Hoogstraten B, George SL, Samal B, Rivkin SE, Constanzi JJ, Bonnet JD, Thigpen T, and Braine H. Combination chemotherapy and Adriamycin in patients with advanced breast cancer. Cancer 38:13-20, 1976. 26. Muss HB, White DR, Cooper MR, Richards F, and Spurr CL.

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Adjuvant Therapy of Breast Cancer by Larry Norton (auth.), I. Craig Henderson (eds.)


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